NOW Foods Aloe Vera 10,000 mg provides highly concentrated aloe vera inner leaf gel in a convenient softgel — equivalent to 10,000 mg of fresh aloe gel per capsule, making it one of the most potent aloe supplements available. Aloe vera inner leaf gel contains acemannan, a bioactive polysaccharide with demonstrated immune-modulating, prebiotic, and gut-soothing properties. Research supports aloe vera for digestive health including GERD, IBS, and intestinal permeability, as well as immune function, blood sugar regulation, and antioxidant protection. The inner fillet gel (not the whole leaf, which contains harsh anthraquinone laxatives) is the preferred form for internal use. NOW Foods uses inner leaf gel only, concentrated 200:1 and standardized for acemannan content, manufactured in their GMP-certified facility.