NOW Foods Vegetarian Glucosamine & MSM provides two of the most studied natural compounds for joint health support in a vegetarian-suitable formula. Standard glucosamine is derived from shellfish, making it unsuitable for vegetarians — NOW Foods uses vegetarian glucosamine sourced from fermented corn, providing the same sulfate form that has been clinically studied for cartilage support without any shellfish. Glucosamine sulfate provides the building blocks for glycosaminoglycan synthesis in cartilage, while MSM (methylsulfonylmethane) contributes sulfur for collagen and cartilage structure and has independent anti-inflammatory properties. Together these two ingredients address joint comfort from complementary angles — structural support and inflammation modulation. Each dose provides a clinically relevant amount of both compounds. GMP-certified and tested for purity.