Carnosine: Anti-Aging To End Old Age?
Carnosine and The Future Of Anti Aging, Will We Live To 150?
There are plenty of anti-aging products on the market these days. There is one that is getting a lot of press right now and that is carnosine. Not to be confused with L-carnitine, carnosine is actually a dipeptide, a combination of the two amino acids beta-alanine and histidine. It protects us not just from physical signs of aging, such as wrinkles and age spots, but also from the neurodegenerative effects. These can lead to such debilitating conditions as dementia and Alzheimer's disease.
Inhibition Of Advanced Glycation End Products
Carnosine addresses the biochemical paradox of life: the elements that make and give life—oxygen, glucose, lipids, protein, trace metals—also destroy life in ways that are by carnosine. It protects against their destructive sides through potent antioxidant, anti-glycating, aldehyde quenching and metal chelating actions.
Carnosine's role in the anti-aging process is mostly due to its ability to protect proteins. Unfortunately, proteins tend to undergo destructive changes as we age, due largely to oxidation and interactions with sugars or aldehydes. These interrelated protein modifications include oxidation, carbonylation, cross-linking, glycation and advanced glycation end product (AGE) formation.
They figure prominently in the processes of aging. Also consider its familiar signs such as skin aging, cataracts and neurodegeneration. Studies show that carnosine is effective against all these forms of protein modification.
What Happens When Cells Divide?
Every time our cells divide, which they do throughout our lifetime, they age. Older cells are less efficient at performing the functions for which they are designed, are less efficient at creating energy and removing by products. Inefficient function of older cells leads to buildups of toxic by products and cross-linked proteins. These are associated aging skin (wrinkles and liver spots), cataracts, and build-up of plaque in the brains of Alzheimer's patients.
After about 60 divisions, cells stop reproducing and are just alive, waiting for death. However, carnosine, has the ability to rejuvenate older cells, acting as an anti-aging agent from within our cell structure.
THE ANTIOXIDANT VALUE OF CARNOSINE
As an antioxidant, carnosine potently quenches that most destructive of free radicals. These are the hydroxyl radical, as well as superoxide, singlet oxygen and the peroxyl radical. Surprisingly, carnosine was the only antioxidant to significantly protect chromosomes from oxidative damage due to 90% oxygen exposure.
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