Health Benefits of Omega 3 Smoothie Squeeze

It should be no surprise that one of the most popular supplements these days is omega-3 fish oil. But most of the products available are in softgel form, which can be difficult to swallow—and difficult to digest as well. This can lead to problems like fish burps and the lack of absorption means fewer benefits from otherwise good quality fish oils.  This is where Omega 3 Smoothie Squeeze comes in!

Long known for their Omega-3 squeeze product, Coromega have come out with their brand new Big Squeeze line. Big Squeeze is a smoothie-like product available in a 16 oz pouch. It comes in three different flavors—lemon, mango and orange. The orange flavor also contains 2000 IU of vitamin D3.

Why choose Coromega Omega-3? What sets them apart?

• 300% better absorption than softgel pills, clinically proven.
• Delicious and easy to digest, with no fishy aftertaste or fishy burps
• Purity – fish oil from small, deep, cold-water fish, molecularly distilled and 3rd party tested
• 1 Coromega Squeeze pouch = full National Institutes of Health recommended day’s dose of Omega-3 (so much easier than taking multiple softgels a day!)

The omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have properties important in nutrition and disease management. Presently fish oil (FO) supplementation relies on capsular triglyceride, but novel delivery systems are emerging. Moreover, flavored emulsified lipid preparations provide a simplified approach to fish oil delivery.

Advantages in Digestion?

Oil in water emulsions are hypothesized to possess advantages in the digestion and absorption of their fatty acids thus increasing the “bioavailability” of the active components. A randomized, crossover designed study compared absorption kinetics of EPA and DHA in 10 subjects consuming 5g (4g of fish oil) of an emulsified fish oil (Coromega®) or the equivalent of the parent oil (4g of fish oil) in capsular form. Blood was obtained at 0, 2, 4, 8, 24 and 48 hours and a tolerance questionnaire was completed at 4 hours post ingestion.

Peak absorption at 8 hours was assessed. Emulsified fish oil promoted increased bioavailability of omega-3 fatty acids with enhanced area under the curve (AUC) through 8 hours. The AUC (% FFA x min) was statistically significant for total omega-3 fatty acids (emulsified FO vs. parent FO, respectively) 1102 ± 23, 319 ± 13 (p = 0.012), EPA 771 ± 161, 314 ± 82 (p = 0.001), and trended toward significance for DHA 393 ± 29, 70 ± 16 (p = 0.18). Subjects reported no tolerance problems with the emulsified lipid preparation compared to mild reports of “fishy burp” with the capsular triglyceride. Furthermore, oil in water emulsions are a highly bioavailable, highly tolerable method of delivery for long chain omega-3 fatty acids from fish oil.

Omega-3 Background

The omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have properties important in nutrition and disease management.

1. Presently fish oil supplementation relies on capsular triglyceride but novel delivery systems are emerging.
2. Flavored emulsified lipid preparations provide a simplified approach to fish oil delivery.
3. Oil in water emulsions are hypothesized to possess advantages in the digestion and absorption of their fatty acids thus increasing the “bioavailability” of the active components.

Hypothesis and Specific Aims for Omega-3 Absorption

Hypothesis: Emulsified triglyceride absorbs faster and to a greater extent compared to a similar dose of the parent triglyceride based on its pre-emulsified state.

Specific Aims:

• To evaluate the effects of feeding a single dose, 4g fish oil (5g Coromega®), of emulsified lipid containing EPA and DHA from fish oil on plasma fatty acids over a 48 hour period.
• To evaluate the extent and rate of absorption of EPA and DHA in healthy subjects fed equivalent doses of fish oil from either a emulsified triglyceride versus a encapsulated triglyceride of similar EPA and DHA dosages.

Omega-3 Study Design

A randomized and crossover design with 10 subjects

• Healthy adults ages 18 to 60
• Body mass index between 22 and 32 kg/m2
• Medical history demonstrating good health
• Nonsmokers
• Consumption of a typical American diet with no unusual dietary habits
• Willingness to comply with the study protocol

Treatments

• Active: 5 g (4 g of fish oil) of Coromega®
• Placebo: 4 g of parent oil

Assessment of absorption kinetics of EPA and DHA

• Plasma obtained at baseline, 2, 4, 8, 24 and 48 hours
• Peak absorption at 8 hours was assessed in total phospholipid

RESULTS

Summary And Conclusions

Summary

Emulsified FO promoted increased bioavailability of omega-3 fatty acids with enhanced area under the curve (AUC) through 8 hours.

The AUC (% FFA x min) was statistically significant for Total omega-3 fatty acids (emulsified FO vs. parent FO, respectively) 1102 ± 23, 319 ± 13 (p = 0.012), EPA 771 ± 161, 314 ± 82 (p = 0.001).

DHA trended toward significance for 393 ± 29, 70 ± 16 (p = 0.18).

As a result, subjects reported no tolerance problems with the emulsified lipid preparation.  This compares to mild reports of “fishy burp” with the capsular triglyceride.

Conclusions

Oil in water emulsions are a highly bioavailable, highly tolerable method of delivery for long chain omega-3 fatty acids from fish oil.

Coromega's Big Squeeze is the pick of the week here at Peach Vitamins in Atlanta. If you are interested in this product, please feel free to stop by or give us a call at 404-2 66-9115. We would be happy to answer any questions you might have about Coromega Omega-3 or any other supplements.